How It Works

KogniZen's various potent ingredients together enable synergistic action on several levels at once. Our Objective is to help you be at your MAX. Let us show you how we intend to do so.

PART 1: THE TACTICS

When you take KogniZen, the fastest ingredients to get to work are Caffeine & L-Theanine. Everyone knows what caffeine is and how it increases energy, focus, and alertness, so we'll skip the explanation and go right ahead into L-Theanine.

L-Theanine is primarily found in Green & Black Tea and is known to significantly increase relaxation, thus countering any jittery effects the caffeine can cause, without decreasing the alertness caused by caffeine! We want you to be energetic, but not anxious. This wonderfully synergistic effect of Caffeine and L-Theanine goes beyond just smoothing out the negative side-effects of caffeine, as L-Theanine also boosts Caffeine's positive effects.

Together, caffeine & L-Theanine enhance performance in terms of attention switching (selective attention), the ability to ignore distraction, and short-term memory retention.1

The individual & synergistic effects of caffeine and L_Theanine start taking place after 30 minutes after taking the capsules, but really kick in after 60 minutes, and their effect usually lasts anywhere between 3-6 hours. We called this combination the “tactics” because these effects are unlikely to be felt the next day unless taken again, i.e. it’s not cumulative.

As you can see, this combined effect is really like 1+1=3... But KogniZen is full of this kind of synergy, so stay tuned as we keep detailing the action plan!

PART 2: THE STRATEGY

This is the "core" part of KogniZen, the creme de la creme, and is comprised of the highest quality extracts of Panax Ginseng, Ginkgo Biloba, Ashwagandha, and Rhodiola Rosea, all of which can be referred to as "adaptogens". These herbs go into effect about an hour or two after you take the capsules and can last well into the early evening, assuming you took the capsules in the morning.

It is hard to say exactly how long their effects last, because these herbs have at least as much impact on your physical body as they do on your mind! Also, they all have significant cumulative effects which come from taking them for several consecutive days. This is why we advise taking KogniZen for 5 consecutive days, to make sure you are getting all the benefits you can get from it!

We also recommend 2 off-days after 5 consecutive days of use is to make sure your body does not build any tolerance towards the herbal extracts, and has some down-time to push its "reset button" in a way, so you can keep benefiting from KogniZen indefinitely.

Each of these herbs has numerous benefits, which is a common attribute of adaptogens, but for the sake of brevity and not making this too long, we will keep it short and focus only on the main benefits.

Korean "Red" Ginseng (also known as Panax Ginseng) is an ancient Asian herb which has been safely used for thousands of years to ward off fatigue, and as a general tonic to invigorate a person and combat physical and mental stress. This is not to be confused with the cheaper American Ginseng which is often mislabeled as Panax Ginseng.

Korean Ginseng has a stimulatory effect which is not jolting the way caffeine is. It’s more of a subtle but long-lasting energy boost which can last for most of the day, and which has been shown to improve aspects of peoples' working memory performance and subjective ratings of calmness.2 Studies have also showed that it helps improve cognitive performance during sustained mental activity3 & mentally demanding tasks.4

Also, the combination of KoreanGinseng & Ginkgo Biloba has been shown to positively affect different aspects of the memory, especially working & long-term memory. One study even estimated the memory improvement effect of the Ginseng+Ginkgo combination to be about 7.5%.5 This is another one of those 1+1=3 combinations we promised ;)

Since we have already mentioned Ginkgo Biloba, we might as well roll with it now. Ginkgo, like Ginseng, has been safely used for thousands of years in Asia and is the most commonly ingested herb for brain health. In addition to its memory benefits6, made stronger by Panax Ginseng as mentioned above, it improves global cognitive functioning. It also increases the blood flow to your brain and is known to exhibit strong neuropretective effects.7

We now come to Ashwagandha, which has its roots in ancient Ayurveda. When developing KogniZen, we added Ashwagandha as our main “shield wall” against stress and anxiety, both immediate & long-term (chronic).

In one study, Ashwagandha significantly reduced scores on all stress-assessments and decreased cortisol, the main stress hormone by up to 27.9% (using 300mg Ashwagandha)8, and again by up to 30.5% in another study (using 500mg Ashwagandha)9, following supplementation with the herb for 60 days! KogniZen contains 450mg Ashwagandha per serving ;)

It’s also important to note that no serious adverse effects were reported in the above studies.

We have all experienced the crippling effect of anxiety at one point or another, so it’s no wonder that yet another study found Ashwagandha can help with both anxiety and depression.10

We concluded that KogniZen will not be what we want it to be without Ashwagandha!

Finally, we come to Rhodiola Rosea. This herb is a spearhead on several fronts. Rhodiola’s strongest attribute is anti-fatigue, with an even stronger effect than the anti-fatigue effect of Korean Ginseng. And yes, you can bet there will be an anti-fatigue 1+1=3 synergy taking place here ;). This herb is going to be rooting for you on those days when you haven't had much sleep. Rhodiola’s anti-fatigue.

In a randomized trial, supplementation with Rhodiola Rosea for just 5 days significantly reduced total fatigue and improved well-being of military cadets when measured 2 hours after ingestion, and again at the end of the trial. Capacity for mental work significantly increased relative to Placebo. The Rhodiola Rosea dose used in this study ranged between 370-555mg (KogniZen contains 435mg/serving).

A similar conclusion was drawn by a double-blind study, where 2 weeks of Rhodiola Supplementation at 170mg given to healthy physicians on night duty significantly reduced fatigue and was able to improve performance on work-related tasks by approximately 20%.12

Rhodiola appears to also possess potent anti-stress attributes. A study found that 4 weeks of 200mg Rhodiola supplementation twice daily is safe and effective in improving life-stress symptoms to a clinically relevant degree, again without any serious side-effects being reported!13 This effect acts synergistically with Ashwagandha’s anti-stress effects. Wait for it… 1+1=3!

But don’t think that this is all Rhodiola Rosea can do! In a clinical trial, and after 42 days supplementation of 340-680mg Rhodiola SHR-5 extract, patients suffering from a current mild to moderate depression saw their symptoms reduced by up to 50% and a degree of improvement of 30%-35%, and again with no serious side effects noted!14

PART 3: THE BACK OFFICE

These are the guys who don't make a lot of noise, but make sure things keep running smoothly in the long-term. I am referring to the B vitamins contained in KogniZen. In case you have not noticed, some of these B vitamins are not the same as the ones found in your multivitamin. We have used the special active Pyridoxyl-5-Phosphate & methylcobalamin instead of the usual pyridoxine (for Vitamin B6) and cobalamin (for vitamin B12). These active forms are not commonly used due to being more expensive, but they are better absorbed by your body. These B vitamins contribute to normal psychological function, a healthy nervous system, and the reduction of tiredness & fatigue.


Disclosure: The author was under the influence of KogniZen at the time of writing this article.

1 Owen, G., Parnell, H., De Bruin, E. and Rycroft, J. (2008). The combined effects of L-theanine and caffeine on cognitive performance and mood. Nutritional Neuroscience, 11(4), pp.193-198.
2 Reay, J., Scholey, A. and Kennedy, D. (2010). Panax ginseng (G115) improves aspects of working memory performance and subjective ratings of calmness in healthy young adults. Human Psychopharmacology: Clinical and Experimental, 25(6), pp.462-471.
3 Reay, J., Kennedy, D. and Scholey, A. (2005). Single doses of Panax ginseng (G115) reduce blood glucose levels and improve cognitive performance during sustained mental activity. Journal of Psychopharmacology, 19(4), pp.357-365.
4 Reay, J., Kennedy, D. and Scholey, A. (2006). Effects of Panax ginseng, consumed with and without glucose, on blood glucose levels and cognitive performance during sustained ‘mentally demanding’ tasks. Journal of Psychopharmacology, 20(6), pp.771-781.
5 Wesnes, K., Ward, T., McGinty, A. and Petrini, O. (2000). The memory enhancing effects of a Ginkgo biloba/Panax ginseng combination in healthy middle-aged volunteers. Psychopharmacology, 152(4), pp.353-361.
6 Kaschel, R. (2011). Specific memory effects of Ginkgo biloba extract EGb 761 in middle-aged healthy volunteers. Phytomedicine, 18(14), pp.1202-1207.
7 Cognitive Performance, SPECT, and Blood Viscosity in Elderly Non-demented People Using Ginkgo Biloba. (2003). Pharmacopsychiatry, 36(4), pp.127-133.
8 Chandrasekhar, K., Kapoor, J. and Anishetty, S. (2012). A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of Ashwagandha root in reducing stress and anxiety in adults. Indian Journal of Psychological Medicine, 34(3), p.255.
9 Auddy, B., Hazra, J., Mitra, A., Abedon, B., Ghosal, S. (2008). A standardized withania somnifera extract significantly reduces stress-related parameters in chronically stressed humans: A double-blind randomized, placebo-controlled study. JANA, 11(1), p.50-56.
10 Andrade, C., Aswath, A., Chaturvedi, SK., Srinivasa, M., and Raguram, R. (2000). A double-blind, placebo-controlled evaluation of the anxiolytic efficacy of an ethanolic extract of withania somnifera. Indian Journal of Psychiatry, 42(3), p.295-301.
11 Shevtsov, V., Zholus, B., Shervarly, V., Vol'skij, V., Korovin, Y., Khristich, M., Roslyakova, N. and Wikman, G. (2003). A randomized trial of two different doses of a SHR-5 Rhodiola rosea extract versus placebo and control of capacity for mental work. Phytomedicine, 10(2-3), pp.95-105.
12 Darbinyan, V., Kteyan, A., Panossian, A., Gabrielian, E., Wikman, G. and Wagner, H. (2000). Rhodiola rosea in stress induced fatigue — A double blind cross-over study of a standardized extract SHR-5 with a repeated low-dose regimen on the mental performance of healthy physicians during night duty. Phytomedicine, 7(5), pp.365-371.
13 Edwards, D., Heufelder, A. and Zimmermann, A. (2012). Therapeutic Effects and Safety of Rhodiola rosea Extract WS® 1375 in Subjects with Life-stress Symptoms - Results of an Open-label Study. Phytotherapy Research, 26(8), pp.1220-1225.
14 Darbinyan, V., Aslanyan, G., Amroyan, E., Gabrielyan, E., Malmström, C. and Panossian, A. (2007). Clinical trial ofRhodiola roseaL. extract SHR-5 in the treatment of mild to moderate depression. Nordic Journal of Psychiatry, 61(5), pp.343-348.